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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374feb493abc7b3d977b2db2db3ce1763940d478b0d99b8a75d41c6662a24b3d' 
  AND token = 'sNhINmM0xRLq8RY+QWlqdtoE9I6V+1dWSL7+vNscTcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}