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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d4ff3d402740b7c5f139708bc5ce2eedb186c20e3811ca41b4b667f408b789' 
  AND token = 'WGgCdPB/nrUWTHujRIOtvfUf5zkD+F9rfnDxpVfAs8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}