SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffcf7d0d17b5b3adc7e243ddd7a6db356f29fe152854436c97eab1253b2641d1' 
  AND token = 'xIdTNdrGuizr2GFzId6tCbUdBRaXaOGN+qWTm/6O9xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}