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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61ab942f1ae55c3ed1c002c09c037721799a5253d8bb1f267ecda30eee807e6c' 
  AND token = 'F6xlMEmvt8Pb5gg3rNrUhHk4sQnwznOq7hhkXsFS6Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}