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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b4db55ec417c17753922cd07e5d90c6939a8fabbdffee33083d1a7a775f00ee' 
  AND token = 'hq8sM3JdbHZjN7UuisJSTUoaeS66ZsAsyWMYBeHy6sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}