SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c244911ef742ffbdb734c3c0b569bbf37828cab1a4fc1e402e530fb0367f2d10' 
  AND token = '3m6uQL2mW518EjfHx1M5bPB3Cf9XkoDim5d2IuWFSiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}