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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e07a1d8e5b7ec07238b5eb21ffff3fb9f11e97d7ddbf2b50e805607d6ab4b1f' 
  AND token = 'QFx4GknDT2+JAGL/GParX3EVgirR44MiVvddGHF+Apw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}