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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b03b6d73b47c267449290943d7e63ee67f8befe33633a36d3dcfa221ce412b37' 
  AND token = 'aePCQQSs9ffC5kVCXfKptobWBP8VFdzQ8BQ/uM69B60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}