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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dedf261f52b2f9ced045d295bc4bf65e4a7bb4f6c740e828cdd2b74ba4e473a' 
  AND token = 'QakbC20NBFQpTbWKrgGPCbdzh3191cLZ4/BqkHCS7Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}