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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fbc0be6cfcd0c292d9a8e68703097cf1432779a1b0c165663c1af7d6e1c842' 
  AND token = 'WymwDqIP6tdKQD0ujRpdY0Auj7r2Bz9efrrRVk4CKnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}