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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43c029f73855497e7a04c9535c4b54464ed51601c3b1555767dd2bdfdddf894' 
  AND token = '6ZGEHMUQNHI9L/6A8ZzL9ND9aFM0X3+dA8adZBoOw88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}