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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89ac18d510a984dbb2797d2c6200939ae5f0eda68f1c7abbcd9bd0273b60e0b9' 
  AND token = '2bIlUqG4GdN4gaH/4p7gs+gB4OuKLQVDHd9zASSJoTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}