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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d5dc9501c1bc031e8bc49f4417fd71976825d92e1a28adc41a60c11f66b796' 
  AND token = 'cpfZS+h8u28DXrx+GK91nx6u9xoL+6CcOeoKL15AZVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}