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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9526fb3e63e75c41827d8be1a22f3f16e54c61ce4ba5014fd25ddd9fed4ecb' 
  AND token = 'w9BfQZbzzQSJhvwXEh0zqo4YGNfllosIZEtt8OC0t2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}