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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51134dd45d4b6ae9a8663ea515e9656b29aaa46e7be0ffb0dc38897ba5d7da1c' 
  AND token = 'SZkXtORWhmgEeiNOHMCFxenELo7g+tUxqkrJIqz5+dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}