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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0693362322db0e236b9c9f64518b07e195d51aa09856777cc2b2286ed5c3450' 
  AND token = 'vOcW2Kfpq8/3QMgSHrV7c/k6/CaFLFWBamcd+xCMHas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}