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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0deaf2684d7f138c0e634a646769ba3ca364855e04e2dd541f0fa80f2c8d2297' 
  AND token = 'ZTBFZmYFnSvdl0YAEnAc4yEhX6rvpfEc4QOGrn4+Lao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}