SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a67d4d752b385516290c6435bc62c9ea4620401f95fbef5fc8dadf431f8b95' 
  AND token = 'VjC2OrKdMcel18EnCfLxG29tnmiPH134zYidrPTwPtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}