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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451f0e365cbcb8906536ceddedbd13af91f4b425952abba72074455b77d4edca' 
  AND token = 'x0VfNdd8KRDXs+8M7+zwGkueQh9VyTdqx71H1G+Jc2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}