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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cecda1b7fb1b33e53a7de09e26395ef657205b9218a334504d515c944fe0917d' 
  AND token = 'fx++MqulOOn9Ux4No14MOSLA5pcqCLpYsJ2UcX9hgUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}