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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1f8c26e2cfb9f79115684f6d2c8487f15bd6022fa4d826de079de7ea3ea89d1' 
  AND token = 'mIR37p+rMH59mIeC84VQL+Cz9aVtZ5ROLBoVbVodCcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}