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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f2673200dcee1e4e5eed3490fd899a43d4216d6ecb9c5bf509e41ba5f1b5e44' 
  AND token = 'uCqVSsgpEBMsatJ6Hxxn8h6LQulYQk9P+g2o4ZuYr8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}