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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1def56ccf41d099d0087e1944418bb476a1cd5570b00e788b0b29f93c0a321f3' 
  AND token = 'OicB+rnumF2da4m6+IZAMarTE9bwVisF1rnvhAof6YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}