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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ba50002e75ef079c5953cf3bf3d1a5e8ebe521519483e5c4f6970286a42c2f' 
  AND token = 'zdwtgt3/cH8Lv8SjyV0lMXBj4/9Es+2iz8CubTtW3h0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}