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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c15f7e26c2a246c38cc95aceed86324042867c6e01755f43957636ce5f6d82f' 
  AND token = '951gMFakl6aqpyL2bDMsGpT/XG4Txmg+wCqN38kerpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}