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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e321bb477d3dcdff61647a6a321d8630e40226b563fbb71d67a2bb26c107add5' 
  AND token = 'ycaLOGqWVMfG81ueipgESS/klh8teAFAU1H/8noDVGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}