SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e9cf2d91a4c7c60e2b27db766f99616b1ccc1ae2aae989269dacc4dfb44656' 
  AND token = 'lDmJCUmYPd+brTtv284XH94Z0rsnERmA657uffCSTXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}