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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346d5aa08707637df6645aab3f433f1740334739dd49ccf0aef9271d5dcd72da' 
  AND token = 'NuuA4ZSnxY2Ul/nNyOCkR5Ru8NAmr3kidk/CzHGIXZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}