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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8458c2bd08269e715284fa844286224a2ebf3bc1e18a5caea73dc3bb92b94b61' 
  AND token = 'jScP50aTwcPHWV5EfmQ7D//qGOKtU1z4cY3qwjJ57bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}