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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3505b4f8fdb294eb52b3bd10c09ccd702d6d24ff6c0338e5d61201abdd657a0d' 
  AND token = 'TXjFUASwbRcQ0LP0iWMfl+dXpvOAaFpZlMYmcMNQW04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}