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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de21afa564cefb94ed78e054ae09921b88d84ded80b5f33569dd8786a150a1e9' 
  AND token = '1XtMjCA3ma3B8SsafZSjT/EVp7dOJAsbJICPyR95gaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}