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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4439893d0860947d38dff5decd1e5f1d8b68d3bf8d9209b645c13ae160b4b1' 
  AND token = 'ukEvCUQ6ufG762lMPXG+VojHDKpmiLh0RA2GTR7V1yA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}