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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c00a52a0d8890c8e71b597816fdbe58a611f6f7b46ceb8587704eaae072dec' 
  AND token = 'rz0ob9On5YU6QkILxLKNeGkOAdk5wiGhMbJ6wSSXJFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}