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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1082e866317504531ff67a06ecff8c6bf58ecf6eb787d3db579bfc67fa8309c' 
  AND token = 'ekN1TG/cgeq0e7gGXA7vzle1BB5MYbBmhLflIX/hBqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}