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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '140a9115380a67dedc803a05f043b9b4f360448e0d3424b9ad142811233ee0b8' 
  AND token = 'ynTLXsF3PjtOx7aAcTRX1w9fukZknBTYje22CHoxhHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}