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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522861e990eb9e5c21683eeafdf141384f6dbe6d2716203be118c9cec4e9657d' 
  AND token = 'Hxy+6suYv1fkXNp4eBOJx8x5/rMCI/vfA5ku0DaCcqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}