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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b1a1664a37c50779e021c4b2a954bc35ae38177ff4b24e209afd21c36e4353' 
  AND token = '1G17rHG1RhD7I+Kow1PMJjLIxivTWnuPtyfv35UOKYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}