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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc78140a478607fb5cf32034e743988436bbbd061508605815ad8f8b65d6bb63' 
  AND token = 'gJ0mnfSdGio66qI1t5glvMFtgMdvnT1MCAb85D+X2GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}