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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '700b6cedc08b8f77c12b9ea239002c9c00213c4774b696dec671ebeba645e3c5' 
  AND token = '1Nqxa+X9gPbyq/JoNIVRxuRvzR8aXM9KPMzJB6Xs+kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}