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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc0b0c405d027145dd7eeb8443dc18b2ccff35bc701838b3a979e90f513b40f' 
  AND token = 'qUFpHk+yvUumvazOGIS06Y+BdCYaIDzrw1mSWmt3pVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}