SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294e4f1492b21800c00f966c72a31a6a66c8827b69b96da35d08c85629dbc25f' 
  AND token = 'zlcKMp2ngygL3GlhDLddjH2Ag3hXCAwhvkuq8IlaSk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}