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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ba67227ed2888a8992e69535b5fa3421e5bd0d040b4155ce3b43baf3ca41720' 
  AND token = 'Srz7y7Sgzmuq8iJOufHIhu9oG6jArTUun5H61JqyTK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}