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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4e1a7b9e9180681ba3b6445c26c2f73f381d55864a968cac870421fea8c18c8' 
  AND token = 'iVHxtuVjWMbqG7lMdx5h/UuASmaPpRSZU/5qSGOZiGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}