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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af04f3f654c827f482ebf6967ec575b99c9538c17bba884608ae491844fccf39' 
  AND token = '5iRDYx/zyVakSvGyaWbjZTyiCz9TJm01xa2bzN+JKOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}