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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb6a12e166fed28b44ba1be7ebc27a01b5f35b9e42a07a5f860469c0b234d30' 
  AND token = 'UWC+7HkYjLmkCC8NVqwfwQXbGc6JL+c1YOMmGJOQavQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}