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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '853b344a8beb820c2dd2ad17edcc6d72b06d6113526fabfef7f0847fe47049f6' 
  AND token = 'RLdj48Dy7+Pr2x9mH0hgqd8iTxgqutz+kk78F18i2Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}