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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45393e72526fc633e2baa9d1adc43ea6472cfbaf4379da66ca69bcfe98f3aed5' 
  AND token = '/Z1fFmH1vKEod61NdIrO7829blrm1NSmCtLGd+XK+pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}