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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd294c8b939895bef5f644a462b5556b6d65d1fcced21b5b2c2b93442301aa2aa' 
  AND token = 'vcPnzAV0xNdyIMpCP0xhzANX+eoXfJPXuSlfRuqd2aY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}