SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f26e36e1f378d97a052347ff0135f1d798cfdff1fb1f36cc4ef33171e89365' 
  AND token = 'OQfcBvCHew3hcewllyrLxpUozRPVzDLyKAvAcZ2bJS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}