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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '664c1f84072da399866343ca115edf4a3258699928c8fbcc39a578b1f770281b' 
  AND token = 'xnudUZWk1hyY0HEpbI41Ev+X4DFHuTvKnoxV04EcsNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}